Walk to Plazuela San Luis along Templeman and Almirante Montt. Walk a bit along Avenida Alemania (past Guillermo Munich) and then take bus 612 towards La Sebastiana (ask the driver if you are not sure). There is no bus stop, so just wave at the driver. Get off at La Sebastiana (Pablo Neruda’s house, at Ricardo Ferrari street) and then walk a couple of blocks to Oda Pacífico restaurant (the point marked Gastronómica Superfish in the map) at Condor 35.
Alternatively you can take a taxi, which should cost around $5.000.